Endocrine Abstracts

Introduction: Diabetic autonomic neuropathy (DAN) and CAN as one of its most common manifestations are serious complication of type 1 and type 2 diabetes mellitus leading to a significant increase in morbidity and mortality. Case presentationA 51-year old male, diagnosed with T2DM for 25 years, complicated by stage III diabetic polyneuropathy, proliferative retinopathy and several amputations on both feet, treated with Metformin (2g/day), Glargine (26 IU/day) and Aspart (21 IU...

Objectives: To assess the prevalence of diabetic peripheral neuropathy (DPN) among futsal players participating in the 2017 edition of the European Futsal Championship for people with diabetes (DiaEuro).Methods: In this cross-sectional study were included 94 amateur/professional futsal player, from 9 European countries. The evaluation was made based on the data extracted from the standard medical certificate completed by each player’s diabetologist....

Polyglandular autoimmune syndromes (PAS) are a heterogeneous group of rare diseases characterized by autoimmune activity against more than one endocrine organ, although non-endocrine organs can be affected. PAS type IV is a rare syndrome characterized by the association of autoimmune endocrine gland disorder which doesn’t fulfill the criteria of PAS type I-III. A 35-years old female diagnosed with alopecia areata and latent autoimmune diabetes of the adult (LADA) one year...

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death. A 59-year old female, under treatment for depressive disorder, diagnosed with type 2 diabetes since 2016 and treated with glargine (20 IU/day), lispro (30 IU/day) insulin and Metformin (500 mg/day) was admitted to the Internal Medicine department via ER (emergency room) for repetiti...

Cutaneous lymphoid hyperplasia (CLH) is a spectrum of benign conditions characterized by reactive B- and T-cell cutaneous lymphocytic infiltrates. The most common presentation of reactive CLH is as a solitary red skin papule, nodule, or plaque but 10–15% of patients present with more generalized or multifocal skin lesions. A 40-year old male, initially diagnosed with type 1 diabetes mellitus (DM), with a family history of autoimmune thyroid disease, vitiligo and type 2 DM...

Background: Resistance to thyroid hormone beta (RTHβ) is an inherited syndrome of reduced tissue responsiveness to thyroid hormones (THs). It is driven in 85% of cases by mutations in the thyroid hormone receptor beta (THRb). The estimated incidence is 1:40.000 to 1:19.000 live births. We report the clinical, laboratory, and genetic analysis of a patient with this disorder.Case report: A 12-year-old boy with a history of Attention-Deficit/H...

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death.Case report: A 65-year-old male, with significant cardiac and pulmonary pathology, diagnosed with type 2 diabetes since 1996 and treated with glargine (70 U/day) and aspart (68 U/day) insulin is admitted to our centre via ER (emergency room) after an episode of...

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death.A 76-years old female, with significant cardiac pathology, diagnosed with type 2 diabetes and treated with Humalog Mix50® 0-0-24 U/day, is admitted to our center via ER (emergency room) after an episode of severe hypoglycemia after administratio...

Introduction: Type 1 diabetes mellitus (T1DM) is the most common form of diabetes in children and young adults. Though T1DM often presents in an acute manner, it may be preceded by a prodromal period, often extending over years.Case report: A 19-year-old male, diagnosed with T1DM at the age of 15, with no insulin treatment, was admitted to our department for high glycemic value (G) of 365 mg/dl on a routine exam at his GP. At diagnosis the patient was as...

In type 1 diabetes athletes, the proper adjustments of insulin doses and carbs intake are essential in order to avoid a hypoglycemic event that could affect the sport performances.The aim of the study was to assess the risk of hypoglycemia, the insulin and glycemic variability in 2 different days (with and without physical activity) in a group of nine players with type 1 diabetes, members of the Romania diabetes futsal team (twice European champion)....